Ethanol → HCID 117966583, 화합물

HRID 931159노트

반응식

HRID 931159 반응식
[Na].[N:2]1([C:7]2([C:10]#[N:11])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[N:3]1.[CH2:12]([OH:14])[CH3:13]>>[N:2]1([C:7]2([C:10](=[NH:11])[O:14][CH2:12][CH3:13])[CH2:9][CH2:8]2)[CH:6]=[CH:5][CH:4]=[N:3]1

참가 물질

4

반응물 3

HCID 702Ethanol2회HCID 5360545SodiumHCID 89853797HCID 89853797, 화합물

생성물 1

HCID 117966583HCID 117966583, 화합물

반응 조건

온도
70 °C

실험 절차

Sodium metal (12 mg, 0.52 mmol) was added to anhydrous ethanol (3 mL) at room temperature and the mixture was stirred for 15 min. 1-(1H-pyrazol-1-yl)cyclopropanecarbonitrile (0.1 g, 0.75 mmol) dissolved in ethanol (2 mL) was added and the reaction mixture was heated to 70° C. for 90 min. The resulting solution was used without further purification.

후처리

  1. additionwas added
  2. customThe resulting solution was used without further purification

출처 및 근거

ORD 기록
ord-3cabb66fe334417aa947b316315a861e
출처 데이터셋
uspto-grants-2016_03
특허 번호
US09296745B2

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