1,1-Dichloroethane → 1-[3-(6-Fluoro-1,2-benzoxazol-3-yl)phenoxy]-3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-ol

반응식

[Cl:34][CH:35]([Cl:36])[CH3:37].[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6](-[c:9]3[cH:10][c:11]([O:15][CH2:16][CH:17]4[O:18][CH2:19]4)[cH:12][cH:13][cH:14]3)[n:7][o:8]2)[cH:20][cH:21]1.[N:22]1([c:28]2[n:29][cH:30][cH:31][cH:32][n:33]2)[CH2:23][CH2:24][NH:25][CH2:26][CH2:27]1>>[F:1][c:2]1[cH:3][c:4]2[c:5]([c:6](-[c:9]3[cH:10][c:11]([O:15][CH2:16][CH:17]([OH:18])[CH2:19][N:25]4[CH2:24][CH2:23][N:22]([c:28]5[n:29][cH:30][cH:31][cH:32][n:33]5)[CH2:27][CH2:26]4)[cH:12][cH:13][cH:14]3)[n:7][o:8]2)[cH:20][cH:21]1

참가 물질

반응물 3

HCID 63651,1-Dichloroethane

HCID 887471-(2-Pyrimidinyl)piperazine

HCID 724658216-Fluoro-3-[3-(oxiran-2-ylmethoxy)phenyl]-1,2-benzoxazole

생성물 1

HCID 179062741-[3-(6-Fluoro-1,2-benzoxazol-3-yl)phenoxy]-3-(4-pyrimidin-2-ylpiperazin-1-yl)propan-2-ol

출처 및 근거

ORD 기록: ord-19f40b952f664beb93e4331e9e05bd38
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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