Ammonia → Ethyl 4-chloro-6-ethoxy-7-methyl-1,8-naphthyridine-3-carboxylate

반응식

[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]2[c:7]([OH:20])[c:8]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:9][n:10][c:11]2[n:12][c:13]1[CH3:14].[NH3:21].[P:22]([Cl:23])([Cl:24])([Cl:25])=[O:26]>>[CH2:1]([CH3:2])[O:3][c:4]1[cH:5][c:6]2[c:7]([Cl:24])[c:8]([C:15](=[O:16])[O:17][CH2:18][CH3:19])[cH:9][n:10][c:11]2[n:12][c:13]1[CH3:14]

참가 물질

반응물 3

HCID 222Ammonia

HCID 24813Phosphorus oxychloride

HCID 178469690Ethyl 6-ethoxy-4-hydroxy-7-methyl-1,8-naphthyridine-3-carboxylate

생성물 1

HCID 23198600Ethyl 4-chloro-6-ethoxy-7-methyl-1,8-naphthyridine-3-carboxylate

출처 및 근거

ORD 기록: ord-80e1a5ca588c4bad811430a5f8587634
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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