Acetate → 4-[2-(4-Morpholin-4-yl-phenylamino)-pyrrolo[2,1-f][1,2,4]triazin-7-yl]-piperidine-1-carboxylic acid tert-butyl ester

HRID 941265

반응식

[Br:20][c:21]1[cH:22][cH:23][c:24]2[cH:25][n:26][c:27]([NH:30][c:31]3[cH:32][cH:33][c:34]([N:37]4[CH2:38][CH2:39][O:40][CH2:41][CH2:42]4)[cH:35][cH:36]3)[n:28][n:29]12.[C:43]([CH3:44])([CH3:45])([CH3:46])[O:47][C:48](=[O:49])[N:50]1[CH2:51][CH2:52][C:53]([B:56]2[O:57][C:58]([CH3:59])([CH3:60])[C:61]([CH3:62])([CH3:63])[O:64]2)=[CH:54][CH2:55]1.[C:72]([O-:73])(=[O:74])[CH3:75].[C:77]([O-:78])(=[O:79])[CH3:80].[CH3:81][N:82]([CH3:83])[CH:84]=[O:85].[Na+:65].[Na+:66].[O-:67][C:68](=[O:69])[O-:70].[OH2:71].[Pd+2:76].[c:1]1([P:2]([c:3]2[cH:4][cH:5][cH:6][cH:7][cH:8]2)[c:9]2[cH:10][cH:11][cH:12][cH:13][cH:14]2)[cH:15][cH:16][cH:17][cH:18][cH:19]1>>[c:21]1([CH:53]2[CH2:52][CH2:51][N:50]([C:48]([O:47][C:43]([CH3:44])([CH3:45])[CH3:46])=[O:49])[CH2:55][CH2:54]2)[cH:22][cH:23][c:24]2[cH:25][n:26][c:27]([NH:30][c:31]3[cH:32][cH:33][c:34]([N:37]4[CH2:38][CH2:39][O:40][CH2:41][CH2:42]4)[cH:35][cH:36]3)[n:28][n:29]12