Hydrochloric Acid → [5-Cyclopropyl-3-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazol-4-yl]-[4-[2-(hydroxymethyl)pyrrolidin-1-yl]piperidin-1-yl]methanone

HRID 943201

반응식

HRID 943201 반응식
[CH:1]1([c:4]2[c:5]([C:25](=[O:26])[OH:27])[c:6](-[c:19]3[cH:20][cH:21][n:22][cH:23][cH:24]3)[n:7][n:8]2-[c:9]2[cH:10][c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]2)[CH2:2][CH2:3]1.[ClH:28].[ClH:29].[NH:30]1[CH2:31][CH2:32][CH:33]([N:36]2[CH:37]([CH2:41][OH:42])[CH2:38][CH2:39][CH2:40]2)[CH2:34][CH2:35]1>>[CH:1]1([c:4]2[c:5]([C:25](=[O:26])[N:30]3[CH2:31][CH2:32][CH:33]([N:36]4[CH:37]([CH2:41][OH:42])[CH2:38][CH2:39][CH2:40]4)[CH2:34][CH2:35]3)[c:6](-[c:19]3[cH:20][cH:21][n:22][cH:23][cH:24]3)[n:7][n:8]2-[c:9]2[cH:10][c:11]([C:15]([F:16])([F:17])[F:18])[cH:12][cH:13][cH:14]2)[CH2:2][CH2:3]1

참가 물질

4

반응물 3

HCID 313Hydrochloric Acid2회HCID 66901574[1-(Piperidin-4-yl)pyrrolidin-2-yl]methanolHCID 673152275-cyclopropyl-3-pyridin-4-yl-1-(3-trifluoromethyl-phenyl)-1H-pyrazole-4-carboxylic acid

생성물 1

HCID 67314716[5-Cyclopropyl-3-pyridin-4-yl-1-[3-(trifluoromethyl)phenyl]pyrazol-4-yl]-[4-[2-(hydroxymethyl)pyrrolidin-1-yl]piperidin-1-yl]methanone

출처 및 근거

ORD 기록
ord-0e3768fc6f16454796bd7571abfe249d
출처 데이터셋
Validation data from https://doi.org/10.1039/C8SC04228D

연결된 노트

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