Chloroform → 4-[(5-Chloro-2-pyridinyl)methoxy]-1-[4-[2-(3-hydroxypyrrolidin-1-yl)ethoxy]phenyl]pyridin-2-one

반응식

[C:6]([Si:7]([CH3:8])([CH3:9])[O:11][CH:12]1[CH2:13][N:14]([CH2:17][CH2:18][O:19][c:20]2[cH:21][cH:22][c:23](-[n:26]3[c:27](=[O:41])[cH:28][c:29]([O:32][CH2:33][c:34]4[n:35][cH:36][c:37]([Cl:40])[cH:38][cH:39]4)[cH:30][cH:31]3)[cH:24][cH:25]2)[CH2:15][CH2:16]1)([CH3:10])([CH3:42])[CH3:43].[CH2:1]1[O:2][CH2:3][CH2:4][CH2:5]1.[CH:44]([Cl:45])([Cl:46])[Cl:47]>>[OH:11][CH:12]1[CH2:13][N:14]([CH2:17][CH2:18][O:19][c:20]2[cH:21][cH:22][c:23](-[n:26]3[c:27](=[O:41])[cH:28][c:29]([O:32][CH2:33][c:34]4[n:35][cH:36][c:37]([Cl:40])[cH:38][cH:39]4)[cH:30][cH:31]3)[cH:24][cH:25]2)[CH2:15][CH2:16]1

참가 물질

반응물 3

HCID 6212Chloroform

HCID 8028Tetrahydrofuran

HCID 178455090HCID 178455090, 화합물

생성물 1

HCID 684322734-[(5-Chloro-2-pyridinyl)methoxy]-1-[4-[2-(3-hydroxypyrrolidin-1-yl)ethoxy]phenyl]pyridin-2-one

출처 및 근거

ORD 기록: ord-81f5f471903c443eb031bf83a3d91fb9
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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