Hydrochloric Acid → N-(3-azabicyclo[3.1.0]hexan-2-ylmethyl)-2,2,2-trifluoroacetamide

반응식

[C:2]([O:3][C:4](=[O:5])[N:9]1[CH:10]([CH2:15][NH:16][C:17]([C:18]([F:19])([F:20])[F:21])=[O:22])[CH:11]2[CH2:12][CH:13]2[CH2:14]1)([CH3:6])([CH3:7])[CH3:8].[ClH:1].[O:23]1[CH2:24][CH2:25][O:26][CH2:27][CH2:28]1>>[NH:9]1[CH:10]([CH2:15][NH:16][C:17]([C:18]([F:19])([F:20])[F:21])=[O:22])[CH:11]2[CH2:12][CH:13]2[CH2:14]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 312751,4-Dioxane

HCID 765427232-[(2,2,2-Trifluoro-acetylamino)-methyl]-3-aza-bicyclo[3.1.0]hexane-3-carboxylic acid tert-butyl ester

생성물 1

HCID 76542722N-(3-azabicyclo[3.1.0]hexan-2-ylmethyl)-2,2,2-trifluoroacetamide

출처 및 근거

ORD 기록: ord-66b75e6d375947889940004ebaa2fd68
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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