Phosphorus oxychloride → Ethyl 4-chloro-7-fluoroquinoline-3-carboxylate

반응식

[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([OH:17])[c:7]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[cH:8][n:9][c:10]2[cH:11]1.[P:18]([Cl:19])([Cl:20])([Cl:21])=[O:22]>>[F:1][c:2]1[cH:3][cH:4][c:5]2[c:6]([Cl:20])[c:7]([C:12](=[O:13])[O:14][CH2:15][CH3:16])[cH:8][n:9][c:10]2[cH:11]1

참가 물질

반응물 2

HCID 24813Phosphorus oxychloride

HCID 178469609Ethyl 7-fluoro-4-oxo-1,4-dihydroquinoline-3-carboxylate

생성물 1

HCID 14219731Ethyl 4-chloro-7-fluoroquinoline-3-carboxylate

출처 및 근거

ORD 기록: ord-6e44bab5c4904fdcaef9b0fd95da930d
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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