Ethyl orthoformate → 3-(1'-Diethoxymethyl-1',2'-dihydro-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-5'-yl)-5-fluorobenzonitrile

반응식

[CH2:25]([CH3:26])[O:27][CH:28]([O:29][CH2:30][CH3:31])[O:32][CH2:33][CH3:34].[O:1]=[C:2]1[NH:3][c:4]2[cH:5][cH:6][c:7](-[c:16]3[cH:17][c:18]([C:19]#[N:20])[cH:21][c:22]([F:24])[cH:23]3)[cH:8][c:9]2[C:10]12[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2>>[O:1]=[C:2]1[N:3]([CH:28]([O:27][CH2:25][CH3:26])[O:29][CH2:30][CH3:31])[c:4]2[cH:5][cH:6][c:7](-[c:16]3[cH:17][c:18]([C:19]#[N:20])[cH:21][c:22]([F:24])[cH:23]3)[cH:8][c:9]2[C:10]12[CH2:11][CH2:12][CH2:13][CH2:14][CH2:15]2

참가 물질

반응물 2

HCID 31214Ethyl orthoformate

HCID 220193493-(1',2'-dihydro-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-5'-yl)-5-fluorobenzonitrile

생성물 1

HCID 220193783-(1'-Diethoxymethyl-1',2'-dihydro-2'-oxospiro[cyclohexane-1,3'-[3H]indol]-5'-yl)-5-fluorobenzonitrile

출처 및 근거

ORD 기록: ord-b98f0070312c403cab32885381c0e3dd
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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