Acetonitrile → 6-((1-(3-Fluoro-5-(trifluoromethyl)benzyl)piperidin-4-yl)amino)pyridazine-3-carbonitrile

반응식

[CH3:38][C:39]#[N:40].[CH:29]([N:30]([CH:31]([CH3:32])[CH3:33])[CH2:34][CH3:35])([CH3:36])[CH3:37].[Cl:1][c:2]1[cH:3][cH:4][c:5]([C:8]#[N:9])[n:6][n:7]1.[Cl:41][CH2:42][Cl:43].[F:10][c:11]1[cH:12][c:13]([CH2:14][N:15]2[CH2:16][CH2:17][CH:18]([NH2:21])[CH2:19][CH2:20]2)[cH:22][c:23]([C:25]([F:26])([F:27])[F:28])[cH:24]1>>[c:2]1([NH:21][CH:18]2[CH2:17][CH2:16][N:15]([CH2:14][c:13]3[cH:12][c:11]([F:10])[cH:24][c:23]([C:25]([F:26])([F:27])[F:28])[cH:22]3)[CH2:20][CH2:19]2)[cH:3][cH:4][c:5]([C:8]#[N:9])[n:6][n:7]1