Chloroform → Ethyl 4-[(thiazolo[4,5-c]pyridin-2-yl)amino]-1-piperidinecarboxylate

반응식

[CH3:13][S:14](=[O:15])(=[O:16])[c:17]1[s:18][c:19]2[c:20]([cH:21][n:22][cH:23][cH:24]2)[n:25]1.[Cl:26][CH:27]([Cl:28])[Cl:29].[NH2:1][CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH2:6][CH2:7]1>>[NH:1]([CH:2]1[CH2:3][CH2:4][N:5]([C:8](=[O:9])[O:10][CH2:11][CH3:12])[CH2:6][CH2:7]1)[c:17]1[s:18][c:19]2[c:20]([cH:21][n:22][cH:23][cH:24]2)[n:25]1

참가 물질

반응물 3

HCID 6212Chloroform

HCID 100867Ethyl 4-amino-1-piperidinecarboxylate

HCID 157251382-(Methylsulfonyl)thiazolo[4,5-c]pyridine

생성물 1

HCID 14576031Ethyl 4-[(thiazolo[4,5-c]pyridin-2-yl)amino]-1-piperidinecarboxylate

출처 및 근거

ORD 기록: ord-a76a81168b614e7d901a5146878a32cf
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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