1-Methylpiperazine → 2-[2-Hydroxy-4-(4-methyl-piperazin-1-yl)-phenylamino]-8-indan-5-yl-5-oxo-5,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid amide

반응식

[CH2:34]1[CH2:35][CH2:36][c:37]2[cH:38][c:39](-[n:43]3[cH:44][c:45]([C:58](=[O:59])[NH2:60])[c:46](=[O:57])[c:47]4[c:48]3[n:49][c:50]([S:53]([CH3:54])(=[O:55])=[O:56])[n:51][cH:52]4)[cH:40][cH:41][c:42]21.[CH3:27][N:28]1[CH2:29][CH2:30][NH:31][CH2:32][CH2:33]1.[F:16][c:17]1[cH:18][cH:19][c:20]([N+:21]([O-:22])=[O:23])[cH:24][c:25]1[OH:26].[NH2:1][c:2]1[c:3]([OH:15])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1>>[NH:1]([c:2]1[c:3]([OH:15])[cH:4][c:5]([N:8]2[CH2:9][CH2:10][N:11]([CH3:14])[CH2:12][CH2:13]2)[cH:6][cH:7]1)[c:50]1[n:49][c:48]2[n:43](-[c:39]3[cH:38][c:37]4[c:42]([cH:41][cH:40]3)[CH2:34][CH2:35][CH2:36]4)[cH:44][c:45]([C:58](=[O:59])[NH2:60])[c:46](=[O:57])[c:47]2[cH:52][n:51]1