Acetonitrile → 5-bromo-2-[4-[1-[6-(trifluoromethyl)-3-pyridinyl]ethylamino]-7,8-dihydro-5H-pyrido[4,3-d]pyrimidin-6-yl]benzonitrile

HRID 959728노트

반응식

[Br:24][c:25]1[cH:26][cH:27][c:28]([F:33])[c:29]([C:30]#[N:31])[cH:32]1.[CH3:43][C:44]#[N:45].[CH:34]([N:35]([CH2:36][CH3:37])[CH:38]([CH3:39])[CH3:40])([CH3:41])[CH3:42].[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]([CH3:10])[NH:11][c:12]2[c:13]3[c:14]([n:15][cH:16][n:17]2)[CH2:18][CH2:19][NH:20][CH2:21]3)[cH:7][n:8]1)([F:22])[F:23]>>[F:1][C:2]([c:3]1[cH:4][cH:5][c:6]([CH:9]([CH3:10])[NH:11][c:12]2[c:13]3[c:14]([n:15][cH:16][n:17]2)[CH2:18][CH2:19][N:20]([c:28]2[cH:27][cH:26][c:25]([Br:24])[cH:32][c:29]2[C:30]#[N:31])[CH2:21]3)[cH:7][n:8]1)([F:22])[F:23]