Acetic Anhydride → (+/-)-Acetic acid (1SR,3RS,4RS)-3-{[1-(3,4-biscyclopropylmethoxyphenyl)methanoyl]amino}-4-(3,4-dimethoxyphenyl)cyclohexyl ester

반응식

[CH3:37][C:38](=[O:39])[O:40][C:41](=[O:42])[CH3:43].[CH:1]1([CH2:4][O:5][c:6]2[cH:7][c:8]([C:9](=[O:10])[NH:11][CH:12]3[CH:13]([c:19]4[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]4)[CH2:14][CH2:15][CH:16]([OH:18])[CH2:17]3)[cH:29][cH:30][c:31]2[O:32][CH2:33][CH:34]2[CH2:35][CH2:36]2)[CH2:2][CH2:3]1>>[CH:1]1([CH2:4][O:5][c:6]2[cH:7][c:8]([C:9](=[O:10])[NH:11][CH:12]3[CH:13]([c:19]4[cH:20][c:21]([O:27][CH3:28])[c:22]([O:25][CH3:26])[cH:23][cH:24]4)[CH2:14][CH2:15][CH:16]([O:18][C:38]([CH3:37])=[O:39])[CH2:17]3)[cH:29][cH:30][c:31]2[O:32][CH2:33][CH:34]2[CH2:35][CH2:36]2)[CH2:2][CH2:3]1

참가 물질

반응물 2

HCID 7918Acetic Anhydride

HCID 68986614(+/-)-3,4-bis-cyclopropylmethoxy-N-[(1RS,2RS,5RS)-2-(3,4-dimethoxyphenyl)-5-hydroxycyclohexyl]benzamide

생성물 1

HCID 86601278(+/-)-Acetic acid (1SR,3RS,4RS)-3-{[1-(3,4-biscyclopropylmethoxyphenyl)methanoyl]amino}-4-(3,4-dimethoxyphenyl)cyclohexyl ester

출처 및 근거

ORD 기록: ord-47cd776d1f8547ccbb4dd13da36c5984
출처 데이터셋: Validation data from https://doi.org/10.1039/C8SC04228D
DOI: 10.1039/C8SC04228D

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