Hydrochloric Acid → 3-(6-Fluorooxazolo[4,5-b]pyridin-2-yl)-5-[1-(4-piperidyl)pyrazol-4-yl]pyridin-2-amine

반응식

[Cl:37][CH2:38][Cl:39].[ClH:36].[NH2:1][c:2]1[c:3](-[c:26]2[o:27][c:28]3[c:29]([n:30][cH:31][c:32]([F:34])[cH:33]3)[n:35]2)[cH:4][c:5](-[c:8]2[cH:9][n:10][n:11]([CH:13]3[CH2:14][CH2:15][N:16]([C:19]([O:20][C:21]([CH3:22])([CH3:23])[CH3:24])=[O:25])[CH2:17][CH2:18]3)[cH:12]2)[cH:6][n:7]1>>[NH2:1][c:2]1[c:3](-[c:26]2[o:27][c:28]3[c:29]([n:30][cH:31][c:32]([F:34])[cH:33]3)[n:35]2)[cH:4][c:5](-[c:8]2[cH:9][n:10][n:11]([CH:13]3[CH2:14][CH2:15][NH:16][CH2:17][CH2:18]3)[cH:12]2)[cH:6][n:7]1

참가 물질

반응물 3

HCID 313Hydrochloric Acid

HCID 6344Dichloromethane

HCID 67389039Tert-butyl 4-[4-[6-amino-5-(6-fluorooxazolo[4,5-b]pyridin-2-yl)-3-pyridyl]pyrazol-1-yl]piperidine-1-carboxylate

생성물 1

HCID 576871183-(6-Fluorooxazolo[4,5-b]pyridin-2-yl)-5-[1-(4-piperidyl)pyrazol-4-yl]pyridin-2-amine

출처 및 근거

ORD 기록: ord-8c8f187a310c4293b2a7299e5af21550
출처 데이터셋: Training data from https://doi.org/10.1039/C8SC04228D (2/10)
DOI: 10.1039/C8SC04228D

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