Hydrogen Bromide → 3-tert-butoxycarbonyl-7-chloro-6-(pyridin-2-ylmethoxy)-2,3,4,5-tetrahydro-1H-benzo[d]azepine

HRID 962223노트

반응식

[Br:24][CH2:25][c:26]1[n:27][cH:28][cH:29][cH:30][cH:31]1.[BrH:23].[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[c:14]([c:17]([OH:22])[c:18]([Cl:21])[cH:19][cH:20]2)[CH2:15][CH2:16]1.[H-:1].[Na+:2].[O:32]=[CH:33][N:34]([CH3:35])[CH3:36]>>[C:3]([CH3:4])([CH3:5])([CH3:6])[O:7][C:8](=[O:9])[N:10]1[CH2:11][CH2:12][c:13]2[c:14]([c:17]([O:22][CH2:25][c:26]3[n:27][cH:28][cH:29][cH:30][cH:31]3)[c:18]([Cl:21])[cH:19][cH:20]2)[CH2:15][CH2:16]1