Phenol → {3-(Phenoxymethyl)-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanol

HRID 9646

반응식

HRID 9646 반응식
Br[CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:13]=[CH:12][C:11]([C:14]([F:17])([F:16])[F:15])=[CH:10][CH:9]=2)[S:5][C:4]=1[C:18](OCC)=[O:19].[C:23]1([OH:29])[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1>>[O:29]([CH2:2][C:3]1[CH:7]=[C:6]([C:8]2[CH:9]=[CH:10][C:11]([C:14]([F:16])([F:15])[F:17])=[CH:12][CH:13]=2)[S:5][C:4]=1[CH2:18][OH:19])[C:23]1[CH:28]=[CH:27][CH:26]=[CH:25][CH:24]=1

참가 물질

3

반응물 2

HCID 996PhenolHCID 21986402Ethyl 3-(bromomethyl)-5-[4-(trifluoromethyl)phenyl]thiophene-2-carboxylate

생성물 1

HCID 21986289{3-(Phenoxymethyl)-5-[4-(trifluoromethyl)phenyl]thien-2-yl}methanol

실험 절차

Prepared from intermediate 43 and phenol

출처 및 근거

ORD 기록
ord-2e95888c3ff84a0fb8e3c2a881c4f9d9
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091237B2

연결된 노트

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