Water → HCID 21986453, 화합물

HRID 9654

반응식

HRID 9654 반응식
[CH2:1]([O:3][C:4](=[O:22])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][C:16]2[S:17][CH:18]=[CH:19][CH:20]=2)=[CH:9][C:8]=1[CH3:21])[CH3:2].[Br:23]Br.O>C(O)(=O)C>[CH2:1]([O:3][C:4](=[O:22])[CH2:5][O:6][C:7]1[CH:12]=[CH:11][C:10]([O:13][CH2:14][CH2:15][C:16]2[S:17][C:18]([Br:23])=[CH:19][CH:20]=2)=[CH:9][C:8]=1[CH3:21])[CH3:2]

참가 물질

5

반응물 3

HCID 962WaterHCID 24408BromineHCID 21986308Ethyl[2-methyl-4-(2-thien-2-ylethoxy)phenoxy]acetate2회

생성물 1

HCID 21986453HCID 21986453, 화합물

시약·촉매·용매 1

HCID 176Acetic Acid용매

실험 절차

A solution of ethyl[2-methyl-4-(2-thien-2-ylethoxy)phenoxy]acetate (intermediate 69, 0.306 g) in acetic acid (5 ml) was treated with bromine (0.180 g) at ambient temperature and the mixture stirred for 15 minutes. The mixture was poured into water and the resulting suspension extracted with diethyl ether. The organic layer was separated, dried over sodium sulfate and concentrated to give the title compound as a colourless oil.

후처리

  1. extractionthe resulting suspension extracted with diethyl ether
  2. customThe organic layer was separated
  3. dry with materialdried over sodium sulfate
  4. concentrationconcentrated

출처 및 근거

ORD 기록
ord-7637624903df403d86dd6f4ca5b896ea
출처 데이터셋
uspto-grants-2006_08
특허 번호
US07091237B2

연결된 노트

불러오는 중…