HCID 22314545, 화합물 → 1-(3,4-Dihydroxy-2-methoxyphenyl)-2-(1,1-dimethylpropylamino)ethanone

HRID 966095노트

반응식

HRID 966095 반응식
[CH3:1][C:2]([NH:6][CH2:7][C:8]([C:10]1[CH:30]=[CH:29][C:13]2[O:14]C(C3C=CC=CC=3)(C3C=CC=CC=3)[O:16][C:12]=2[C:11]=1[O:31][CH3:32])=[O:9])([CH3:5])[CH2:3][CH3:4]>Cl>[OH:16][C:12]1[C:11]([O:31][CH3:32])=[C:10]([C:8](=[O:9])[CH2:7][NH:6][C:2]([CH3:1])([CH3:5])[CH2:3][CH3:4])[CH:30]=[CH:29][C:13]=1[OH:14]

참가 물질

3

반응물 1

HCID 22314545HCID 22314545, 화합물

생성물 1

HCID 223145401-(3,4-Dihydroxy-2-methoxyphenyl)-2-(1,1-dimethylpropylamino)ethanone

시약·촉매·용매 1

HCID 313Hydrochloric Acid용매

실험 절차

25 g of 2-(1,1-dimethylpropylamino)-1-(4-methoxy-2,2-diphenylbenzo[1,3]dioxol-5-yl) ethanone is refluxed with 50 mL of 15% methanolic hydrochloric acid for 2 hours with stirring. The solvent is distilled off under reduced pressure and the residue is dissolved in acetonitrile and combined with ethyl acetate. The precipitated crystals are suction filtered and washed with acetonitrile and diethyl ether. Yield: 15 g (92%) of the compound as the hydrochloride.

후처리

  1. distillationThe solvent is distilled off under reduced pressure
  2. dissolutionthe residue is dissolved in acetonitrile
  3. filtrationfiltered
  4. washwashed with acetonitrile and diethyl ether

출처 및 근거

ORD 기록
ord-1d0a380a21a44297a99d2ed5dcfd711a
출처 데이터셋
uspto-grants-2005_10
특허 번호
US06951888B2

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