HCID 10910823, 화합물 → Spermine

HRID 968183

반응식

HRID 968183 반응식
C([CH:8]([CH2:24][CH2:25][NH:26][CH2:27][CH2:28][CH2:29][CH2:30][NH:31][CH2:32][CH2:33][CH2:34][NH2:35])[N:9](C(OC(C)(C)C)=O)C(OC(C)(C)C)=O)(OC(C)(C)C)=O.N(CCCI)=[N+]=[N-]>[Pd]>[NH2:35][CH2:34][CH2:33][CH2:32][NH:31][CH2:30][CH2:29][CH2:28][CH2:27][NH:26][CH2:25][CH2:24][CH2:8][NH2:9]

참가 물질

4

반응물 2

HCID 10910823HCID 10910823, 화합물HCID 22610912TriBoc-Spermine

생성물 1

HCID 1103Spermine

시약·촉매·용매 1

HCID 23938Palladium촉매

실험 절차

Monoquaternary spermine containing hydrophilic head-group was prepared in a similar way to compound 3. Briefly, TriBoc-Spermine was reacted with excess of 1-azido-3-iodo-propane in the presence of excess TBA. The resulting quaternarized derivative was hydrogenised under (Pd—C) and Boc protecting group were removed using gaseous HCl in dry methanol.

후처리

  1. customwere removed

출처 및 근거

ORD 기록
ord-7efc57ded6f7404794f1c0a62996d328
출처 데이터셋
uspto-grants-2005_10
특허 번호
US06958325B2

연결된 노트

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