Potassium Hydroxide → Glycerol tris[2-hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]ether

HRID 972021

반응식

HRID 972021 반응식
[CH3:1][C:2]1([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11][C:4]2([NH:8][C:7](=[O:9])[NH:6][C:5]2=[O:10])[CH2:3]1.[O:18]1[CH2:35][CH:19]1[CH2:20][O:21][CH2:22][CH:23]([CH2:29][O:30][CH2:31][CH:32]1[O:34][CH2:33]1)[O:24][CH2:25][CH:26]1[O:28][CH2:27]1.[OH-:36].[K+]>CO>[OH:18][CH:19]([CH2:35][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[CH2:20][O:21][CH2:22][CH:23]([CH2:29][O:30][CH2:31][CH:32]([OH:34])[CH2:33][N:6]1[C:5](=[O:36])[C:4]2([CH2:3][C:2]([CH3:1])([CH3:17])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9])[O:24][CH2:25][CH:26]([OH:28])[CH2:27][N:6]1[C:5](=[O:10])[C:4]2([CH2:3][C:2]([CH3:17])([CH3:1])[N:13]([CH3:14])[C:12]([CH3:16])([CH3:15])[CH2:11]2)[NH:8][C:7]1=[O:9]

참가 물질

5

반응물 3

HCID 14797Potassium HydroxideHCID 25795TriglycidylglycerolHCID 204818537,7,8,9,9-Pentamethyl-1,3,8-triazaspiro[4.5]decane-2,4-dione

생성물 1

HCID 131711585Glycerol tris[2-hydroxy-3-(7,7,8,9,9-pentamethyl-2,4-dioxo-1,3,8-triazaspiro[4.5]dec-3-yl)propyl]ether

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

12.0 g of 7,7,8,9,9-pentamethyl-1,3,8-triazaspiro[4.5]-decane-2,4-dione, 4.1 g of glycerol tris(2,3-epoxypropyl)ether and 1.1 g of potassium hydroxide were reacted in 80 ml of methanol, following substantially the same procedure as in Example 1. The desired Compound No. 177 was obtained in the form of a white powder, having an Rf value of 0.45 on thin-layer chromatography on silica gel using a 4:4:4:1:1 by volume mixture of benzene, ethyl acetate, chloroform, methanol and triethylamine as developing solvent.

출처 및 근거

ORD 기록
ord-92d226cb0e284e6eb5648e6b1e540e68
출처 데이터셋
uspto-grants-1979_07
특허 번호
US04162246

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