반응식
[CH3:1][CH:2]([CH2:4][C@H:5]([NH:9]C([C@@H](O)[C@H](N)CC1C=CC=CC=1)=O)[C:6]([OH:8])=[O:7])[CH3:3]>Cl>[NH2:9][C@H:5]([C:6]([OH:8])=[O:7])[CH2:4][CH:2]([CH3:3])[CH3:1]참가 물질
3
반응물 1
생성물 1
시약·촉매·용매 1
실험 절차
The hydrolysis of bestatin in 6N HCl at 100° C for 18 hours yields L-leucine and an unusual amino acid. The ratio of these amino acids is 1:1. Bestatin gives positive Rydon-Smith and ninhydrin reactions. The amino acid sequence of bestatin shown in the structure was elucidated by fragmentation pattern in mass spectrum of bestatin methyl ester hydrochloride. Thus, the structure of bestatin is (2S,3R)-3-amino-2-hydroxy-4-phenylbutyryl-L-leucine.
출처 및 근거
- ORD 기록
- ord-d933097c8a2a46e685fa1b46a76d973b
- 출처 데이터셋
- uspto-grants-1977_10
- 특허 번호
- US04052449
연결된 노트
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