1-Methylhomopiperazine → 3-Cyano-2-pyridone

HRID 972690

반응식

HRID 972690 반응식
FC1C=CC([C:8]2[NH:9][C:10](=[O:16])[C:11](=[CH:14][CH:15]=2)[C:12]#[N:13])=CC=1.CN1CCCNCC1>CS(C)=O>[O:16]=[C:10]1[NH:9][CH:8]=[CH:15][CH:14]=[C:11]1[C:12]#[N:13]

참가 물질

4

반응물 2

HCID 2283491-MethylhomopiperazineHCID 27652036-(4-Fluorophenyl)-2-oxo-1,2-dihydropyridine-3-carbonitrile

생성물 1

HCID 5775433-Cyano-2-pyridone

시약·촉매·용매 1

HCID 679Dimethyl Sulfoxide용매

실험 절차

From 12.9 g. of 6-(p-fluorophenyl)-1,2-dihydro-2-oxonicotinonitrile and 13.8 g. of N-methylhomopiperazine in 180 ml. of dimethyl sulfoxide, there is obtained 6-[p-hexahydro-4-methyl-1H-1,4-diazepin-1-yl)phenyl]-1,2-dihydro-2-oxonicotinonitrile.

출처 및 근거

ORD 기록
ord-c243a54c7755405bbe0f6fee84b3a5ed
출처 데이터셋
uspto-grants-1977_10
특허 번호
US04053470

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