1-Butanol → Butyl 4-(4,6-bis(trichloromethyl)-s-triazin-2-yl)benzoate

HRID 973810노트

반응식

HRID 973810 반응식
[Cl:1][C:2]([Cl:23])([Cl:22])[C:3]1[N:8]=[C:7]([C:9]([Cl:12])([Cl:11])[Cl:10])[N:6]=[C:5]([C:13]2[CH:21]=[CH:20][C:16]([C:17](Cl)=[O:18])=[CH:15][CH:14]=2)[N:4]=1.C([OH:28])CCC.[C:29]1(C)C=C[CH:32]=[CH:31][CH:30]=1>N1C=CC=CC=1>[Cl:11][C:9]([Cl:10])([Cl:12])[C:7]1[N:8]=[C:3]([C:2]([Cl:23])([Cl:22])[Cl:1])[N:4]=[C:5]([C:13]2[CH:21]=[CH:20][C:16]([C:17]([O:18][CH2:29][CH2:30][CH2:31][CH3:32])=[O:28])=[CH:15][CH:14]=2)[N:6]=1

참가 물질

5

반응물 3

HCID 2631-ButanolHCID 1140TolueneHCID 14473251HCID 14473251, 화합물

생성물 1

HCID 19989297Butyl 4-(4,6-bis(trichloromethyl)-s-triazin-2-yl)benzoate

시약·촉매·용매 1

HCID 1049Pyridine용매

반응 조건

온도
15 °C

실험 절차

4-(4,6-Bis(trichloromethyl)-s-triazin-2-yl)-benzoyl chloride (9 pw) and n-butanol (1 pw) are added to dry toluene (100 pw). The mixture is stirred at 15° C., and 1.9 pw of pyridine is added dropwise. Stirring is continued for 3 hours. The resulting mixture is washed with 2% strength hydrochloric acid, 2% strength sodium hydroxide solution and then with water. After drying of the organic phase over magnesium sulfate, the solvent is removed by distillation, and the residue is recrystallized from ethanol. M.p. 109 to 110° C.

후처리

  1. stirringStirring
  2. washThe resulting mixture is washed with 2% strength hydrochloric acid, 2% strength sodium hydroxide solution
  3. dry with materialAfter drying of the organic phase over magnesium sulfate
  4. customthe solvent is removed by distillation
  5. customthe residue is recrystallized from ethanol

출처 및 근거

ORD 기록
ord-3fc9537ad5844ffca805ef0592a35865
출처 데이터셋
uspto-grants-1991_11
특허 번호
US05064959

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