Toluene → Isoprocarb

HRID 974097

반응식

C(O[C:5]1[CH:10]=CC=[CH:7][C:6]=1O)(C)C.[CH3:12][NH:13][C:14](=[O:18])[O:15][CH2:16][CH3:17].P(Cl)(Cl)(Cl)=O.[C:24]1(C)[CH:29]=CC=C[CH:25]=1>>[CH3:12][NH:13][C:14](=[O:18])[O:15][C:16]1[CH:7]=[CH:6][CH:5]=[CH:10][C:17]=1[CH:24]([CH3:29])[CH3:25]

참가 물질

반응물 4

HCID 1140Toluene

HCID 7752Carbamic acid, N-methyl-, ethyl ester

HCID 209492-Isopropoxyphenol

HCID 24813Phosphorus oxychloride

생성물 1

HCID 17517Isoprocarb

실험 절차

To a solution of 2-isopropoxyphenol (1.38 g, 0.01 mole) and ethyl N-methylcarbamate (1.03 g, 0.01 mole) in toluene (10 ml), was added phosphoryl chloride (1.54 g, 0.01 mole) and refluxed for six hours. The reaction mixture was worked up as described earlier to give 2-isopropylphenyl N-methylcarbamate of the formula (VII) as a solid, crystallised from pet. ether, m.p. 88° C. to 93° C.

후처리

temperaturerefluxed for six hours

출처 및 근거

ORD 기록: ord-1c2836f87b1c471cb665418b0a825c75
출처 데이터셋: uspto-grants-1991_11
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US05066819

연결된 노트

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