Sodium Carbonate → 5-Methyl-2-phenyl-2-hexenal oxime

HRID 975252

반응식

HRID 975252 반응식
[CH3:1][CH:2]([CH3:14])[CH2:3][CH:4]=[C:5]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH:6]=O.[Cl-].[OH:16][NH3+:17].C(=O)([O-])[O-].[Na+].[Na+]>C(O)C.O>[CH3:1][CH:2]([CH3:14])[CH2:3][CH:4]=[C:5]([C:8]1[CH:13]=[CH:12][CH:11]=[CH:10][CH:9]=1)[CH:6]=[N:17][OH:16]

참가 물질

6

반응물 3

HCID 10340Sodium CarbonateHCID 21645Hydroxylamine HClHCID 5760265-Methyl-2-phenylhex-2-enal

생성물 1

HCID 867504445-Methyl-2-phenyl-2-hexenal oxime수율 74.7%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 962Water용매2회

실험 절차

To a solution of 5-methyl-2-phenyl-2-hexenal (5.0 g, 27 mmol) and hydroxylammonium chloride (3.7 g, 53 mmol) in a mixture of 96% ethanol (20 ml) and water (5 ml) was carefully added a solution of sodium carbonate (11.2 g, 106 mmol) in water (30 ml). The resulting mixture was stirred for 2h, the precipitated compound was filtered off and suspended in dichloromethane (500 ml). The suspension was filtered and the solvent evaporated from the filtrate in vacuo to give 4.1 g of 5-methyl-2-phenyl-2-hexenal oxime.

후처리

  1. filtrationthe precipitated compound was filtered off
  2. filtrationThe suspension was filtered
  3. customthe solvent evaporated from the filtrate in vacuo

출처 및 근거

ORD 기록
ord-f1f4eae056ee4b13a00afc32e58d3f69
출처 데이터셋
uspto-grants-1997_03
특허 번호
US05608069

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