Hydrochloric Acid → HCID 178447643, 화합물
반응식
Cl.[CH3:2][N:3]1[C:7]([CH:8]([CH3:15])[CH2:9][CH2:10][C:11]([O:13]C)=[S:12])=[N:6][N:5]=[N:4]1>O>[CH3:2][N:3]1[C:7]([CH:8]([CH3:15])[CH2:9][CH2:10][C:11]([OH:13])=[S:12])=[N:6][N:5]=[N:4]1참가 물질
4
실험 절차
20% aqueous Hydrochloric acid (150 ml) is added to methyl 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thiovalerate (17 g) and the mixture is refluxed for 2 hours. After cooling, the reaction mixture is diluted with water and extracted with chloroform. The chlorofom solution is washed with aqueous saturated sodium chloride solution and dried over magnesium sulfate. Chloroform is distilled off to give 4-(1-methyl-1,2,3,4-tetrazol-5-yl)thio-valeric acid, colorless liquid, nD26 =1.5133.
후처리
- temperaturethe mixture is refluxed for 2 hours
- temperatureAfter cooling
- extractionextracted with chloroform
- washThe chlorofom solution is washed with aqueous saturated sodium chloride solution
- dry with materialdried over magnesium sulfate
- distillationChloroform is distilled off
출처 및 근거
- ORD 기록
- ord-66a854a61ef94e1db8cb2e85e07aefe9
- 출처 데이터셋
- uspto-grants-1987_05
- 특허 번호
- US04663323
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