Tert-Butylamine → Tertiarybutylaminoethoxyethanol
반응식
[C:1]([NH2:5])([CH3:4])([CH3:3])[CH3:2].Cl[CH2:7][CH2:8][O:9][CH:10]([OH:12])[CH3:11].[OH-].[Na+]>CO>[C:1]([NH:5][CH2:7][CH2:8][O:9][CH:10]([OH:12])[CH3:11])([CH3:4])([CH3:3])[CH3:2]참가 물질
5
반응 조건
- 온도
- 150 °C
실험 절차
A solution of 45.63 g (0.625 mole) of tertiary-butylamine and 31 g (0.25 mole) of 2-chloroethoxyethanol in 100 ml of methanol was charged to a 300 ml steel autoclave and heated under autogenous pressure for 1 hour at 150° C. The reactor was cooled and the contents removed. To the homogeneous solution was added 11 g (0.275 mole) of NaOH pellets and the reaction refluxed for 0.5-1 hour, cooled, filtered, vacuum stripped, and distilled. The yield was 31.4 g (78%).
후처리
- temperatureThe reactor was cooled
- customthe contents removed
- temperaturethe reaction refluxed for 0.5-1 hour
- temperaturecooled
- filtrationfiltered
- distillationdistilled
출처 및 근거
- ORD 기록
- ord-1903b4917735466a96b4ea299056fd61
- 출처 데이터셋
- uspto-grants-1987_05
- 특허 번호
- US04665234
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