1,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile → 4-Amino-1,3-dimethyl-1H-pyrazole-5-carbonitrile

HRID 979053

반응식

HRID 979053 반응식
[CH3:1][N:2]1[C:6]([C:7]#[N:8])=[C:5]([N+:9]([O-])=O)[C:4]([CH3:12])=[N:3]1>CO.[Ni]>[CH3:1][N:2]1[C:6]([C:7]#[N:8])=[C:5]([NH2:9])[C:4]([CH3:12])=[N:3]1

참가 물질

4

반응물 1

HCID 965071,3-dimethyl-4-nitro-1H-pyrazole-5-carbonitrile

생성물 1

HCID 123358164-Amino-1,3-dimethyl-1H-pyrazole-5-carbonitrile

시약·촉매·용매 2

HCID 935Nickel촉매HCID 887Methanol용매

실험 절차

Two-hundred and seventy-two g of 1,3-dimethyl-4-nitro-5-cyano-pyrazole was subjected to catalytic hydrogenation in methanol using a Raney nickel catalyst. The catalyst was filtered away and the filtrate concentrated. The product solidified, mp 109°-111° C.

후처리

  1. filtrationThe catalyst was filtered away
  2. concentrationthe filtrate concentrated

출처 및 근거

ORD 기록
ord-80572243f85a460c9c65208bd90fc4a8
출처 데이터셋
uspto-grants-1987_05
특허 번호
US04666908

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