Acrylamide → 2-Vinyloxazoline-4,5-dione hydrochloride

HRID 979264

반응식

HRID 979264 반응식
[C:1](Cl)(=[O:5])[C:2]([Cl:4])=[O:3].[C:7]([NH2:11])(=[O:10])[CH:8]=[CH2:9]>ClC(Cl)C>[ClH:4].[CH:8]([C:7]1[O:10][C:1](=[O:5])[C:2](=[O:3])[N:11]=1)=[CH2:9]

참가 물질

4

반응물 2

HCID 6579AcrylamideHCID 65578Oxalyl chloride

생성물 1

HCID 212839312-Vinyloxazoline-4,5-dione hydrochloride수율 99.7%

시약·촉매·용매 1

HCID 63651,1-Dichloroethane용매

실험 절차

Oxalyl chloride (130 g; 1.02 mol) was charged in a reactor, and a warm solution of acrylamide (71 g; 1.0 mol) in dichloroethane (250 ml) was dropwise added thereto (reaction temperature, 10° to 30° C.). After completion of the dropwise addition, the solvent and excess of the oxalyl chloride were removed by distillation under reduced pressure to obtain 2-vinyloxazoline-4,5-dione hydrochloride (161 g) as a yellow oil. Viscosity, 100,000 cp.

후처리

  1. custom(reaction temperature, 10° to 30° C.)
  2. additionAfter completion of the dropwise addition
  3. customthe solvent and excess of the oxalyl chloride were removed by distillation under reduced pressure

출처 및 근거

ORD 기록
ord-ab210d8767f44196a46aaad63d336125
출처 데이터셋
uspto-grants-1987_05
특허 번호
US04666993

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