Acetic Acid → Phenoxybutylamine acetate

HRID 980868

반응식

HRID 980868 반응식
[O:1]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1.C([N+]#[C-])CCC.[C:19]([OH:22])(=[O:21])[CH3:20]>CO>[C:19]([OH:22])(=[O:21])[CH3:20].[O:1]([CH2:8][CH2:9][CH2:10][CH2:11][NH2:12])[C:2]1[CH:7]=[CH:6][CH:5]=[CH:4][CH:3]=1

참가 물질

5

반응물 3

HCID 176Acetic AcidHCID 76008Butyl isocyanideHCID 1162404-Phenoxybutan-1-amine

생성물 1

HCID 70062463Phenoxybutylamine acetate

시약·촉매·용매 1

HCID 887Methanol용매

실험 절차

In a three-necked flask of 25 ml provided with a magnetic bar, a calcium chloride tube and a dropping funnel, 1.99 gr (0.012 mol) of phenoxybutylamine, 1 gr (0.012 mol) of n-butylisonitrile and 0.72 gr of acetic acid were mixed in 5 ml of methanol. A precipitate of phenoxybutylamine acetate formed. This suspension cooled in an ice bath was added under good agitation with 0.87 gr (0.012 mol) of isobutyraldehyde.

후처리

  1. customIn a three-necked flask of 25 ml provided with a magnetic bar, a calcium chloride tube and a dropping funnel

출처 및 근거

ORD 기록
ord-6736ed9f75254637a52481ecc0d7be4d
출처 데이터셋
uspto-grants-1987_01
특허 번호
US04639468

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