Iodine → 6-(1-fluoroethyl)-5-iodo-4-pyrimidone
반응식
[F:1][CH:2]([C:4]1[N:9]=[CH:8][NH:7][C:6](=[O:10])[CH:5]=1)[CH3:3].[I:11]Cl.II.ClCl>C(O)(=O)C>[F:1][CH:2]([C:4]1[N:9]=[CH:8][NH:7][C:6](=[O:10])[C:5]=1[I:11])[CH3:3]참가 물질
6
실험 절차
To an acetic acid (150 ml) solution of 6-(1fluoroethyl)-4-pyrimidone (56.8 g) was added dropwise under room temperature and stirring an acetic acid solution of iodine monochloride prepared by adding iodine (50.8 g) to acetic acid (500 ml) and blowing chlorine (15 g) thereinto under room temperature and stirring, and the resulting mixture was stirred for 6 hours.
후처리
- customprepared
- stirringthe resulting mixture was stirred for 6 hours
출처 및 근거
- ORD 기록
- ord-4abd0c6191b643289218bc490ab01772
- 출처 데이터셋
- uspto-grants-2005_03
- 특허 번호
- US06867212B2
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