Cyclohexanone → 1-(2-((Tert-butyldimethylsilyloxy)methyl)-4-(trifluoromethyl)phenyl)cyclohexanol

반응식

[Br:1][c:2]1[c:3]([CH2:4][O:5][Si:6]([CH3:7])([CH3:8])[C:9]([CH3:10])([CH3:11])[CH3:12])[cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]1.[CH2:21]([Li:22])[CH2:23][CH2:24][CH3:25].[O:26]=[C:27]1[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]1.[O:33]1[CH2:34][CH2:35][CH2:36][CH2:37]1>>[c:2]1([C:27]2([OH:26])[CH2:28][CH2:29][CH2:30][CH2:31][CH2:32]2)[c:3]([CH2:4][O:5][Si:6]([CH3:7])([CH3:8])[C:9]([CH3:10])([CH3:11])[CH3:12])[cH:13][c:14]([C:17]([F:18])([F:19])[F:20])[cH:15][cH:16]1