Hydrochloric Acid → HCID 22507783, 화합물

HRID 985721노트

반응식

HRID 985721 반응식
COCCOC[C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:14]([S:22]([CH3:25])(=[O:24])=[O:23])[C:15]3[C:20]([CH:21]=2)=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:9][CH:8]=1.Cl.C[OH:28]>>[OH:28][C:7]1[CH:12]=[CH:11][C:10]([C:13]2[N:14]([S:22]([CH3:25])(=[O:24])=[O:23])[C:15]3[C:20]([CH:21]=2)=[CH:19][CH:18]=[CH:17][CH:16]=3)=[CH:9][CH:8]=1

참가 물질

4

반응물 3

HCID 313Hydrochloric AcidHCID 887MethanolHCID 68901562HCID 68901562, 화합물

생성물 1

HCID 22507783HCID 22507783, 화합물

실험 절차

A solution of the product of Step D (1.5 g, 4.0 mmol) in methanol (10 mL) was treated with HCl (10 mL, 4 N in dioxane). The reaction was allowed to stir for 2 hr, concentrated, and purified by silica gel chromatography (methanol:dichloromethane), to afford the title compound (0.93 g).

후처리

  1. concentrationconcentrated
  2. custompurified by silica gel chromatography (methanol:dichloromethane)

출처 및 근거

ORD 기록
ord-82f05794caf94f94b1e4a59dd4a7b25a
출처 데이터셋
uspto-grants-2005_03
특허 번호
US06872834B2

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