3'-Aminoacetophenone → 3'-Acetamidoacetophenone

HRID 986261노트

반응식

HRID 986261 반응식
[C:1](OC(=O)C)(=[O:3])[CH3:2].[NH2:8][C:9]1[CH:10]=[C:11]([C:15](=[O:17])[CH3:16])[CH:12]=[CH:13][CH:14]=1>C1(C)C=CC=CC=1>[C:1]([NH:8][C:9]1[CH:10]=[C:11]([C:15](=[O:17])[CH3:16])[CH:12]=[CH:13][CH:14]=1)(=[O:3])[CH3:2]

참가 물질

4

반응물 2

HCID 74173'-AminoacetophenoneHCID 7918Acetic Anhydride

생성물 1

HCID 3462023'-Acetamidoacetophenone

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

50 ml of acetic anhydride are added in the cold to a suspension of 30 g (0.22 mole) of 1-(3-aminophenyl)ethanone in 200 ml of toluene, and the mixture is stirred for 1 h at room temperature, then heated for 1 h to 60° C. and left to stand overnight. The precipitate obtained is drained, ground in ether and dried.

후처리

  1. temperatureheated for 1 h to 60° C.
  2. waitleft
  3. waitto stand overnight
  4. customThe precipitate obtained
  5. dry with materialground in ether and dried

출처 및 근거

ORD 기록
ord-3b778f1cd77f4826ae9e52573306c1a6
출처 데이터셋
uspto-grants-1987_12
특허 번호
US04711899

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