Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Boron trifluoride etherate → 2-fluoromethyl-3-(2-methyl-4-fluorophenyl)-6-nitro-4(3H)-quinazolinone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Boron trifluoride etherate | HCID 8000 | — |
| 반응물 | N-(2-fluoroacetamido-5-nitrobenzoyl)-2-methyl-4-fluoroaniline | HCID 13376458 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-fluoromethyl-3-(2-methyl-4-fluorophenyl)-6-nitro-4(3H)-quinazolinone | HCID 13376466 | 79.1% |
반응 단계
4.0 g of N-(2-fluoroacetamido-5-nitrobenzoyl)-2-methyl-4-fluoraniline, 3.5 g of boron trifluoride etherate and 30 ml of acetic acid are treated in the same manner as described in Example 1-(2), whereby 3.0 g of 2-fluoromethyl-3-(2-methyl-4-fluorophenyl)-6-nitro-4(3H)-quinazolinone are obtained as colorless prisms.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04714702 |
| 출처 데이터셋 | uspto-grants-1987_12 |
| ORD ID | ord-89313873c7094478aba55d719ab59def |
| 출처 메모 | uspto-grants-1987_12 |