1-Bromopropane → HCID 70149959, 화합물
반응식
[NH:1]1[CH:5]2[CH2:6][CH2:7][CH2:8][CH2:9][CH:4]2[NH:3][C:2]1=[S:10].[Br:11][CH2:12][CH2:13][CH3:14]>C(O)C>[BrH:11].[CH2:12]([S:10][C:2]1[NH:3][CH:4]2[CH2:9][CH2:8][CH2:7][CH2:6][CH:5]2[N:1]=1)[CH2:13][CH3:14]참가 물질
4
실험 절차
1 g of octahydro 2H-benzimidazol-2-thione and 1.3 ml of bromopropane in 20 ml of ethanol are heated under reflux until complete dissolution is obtained. The solvent is evaporated off under reduced pressure, the residue is taken up in a minimum amount of dichloromethane, isopropyl ether is added, the solvents are evaporated off under reduced pressure, the residue is recrystallized from isopropyl ether, the expected product is separated off and dried with a yield of 95%.
후처리
- temperatureunder reflux until complete dissolution
- customis obtained
- customThe solvent is evaporated off under reduced pressure
- additionis added
- customthe solvents are evaporated off under reduced pressure
- customthe residue is recrystallized from isopropyl ether
- customthe expected product is separated off
- customdried with a yield of 95%
출처 및 근거
- ORD 기록
- ord-d2747b8ff70b4a42b863385f2c5a540f
- 출처 데이터셋
- uspto-grants-2002_10
- 특허 번호
- US06459001B1
반응 노트
불러오는 중…