Methyl iodide → 1,3-Benzodioxol-5-amine, N-methyl-

반응식

[CH2:1]1[O:10][C:9]2[CH:8]=[CH:7][C:5]([NH2:6])=[CH:4][C:3]=2[O:2]1.I[CH3:12]>>[CH3:12][NH:6][C:5]1[CH:7]=[CH:8][C:9]2[O:10][CH2:1][O:2][C:3]=2[CH:4]=1

참가 물질

반응물 2

HCID 6328Methyl iodide

HCID 843101,3-Benzodioxol-5-amine

생성물 1

HCID 106069191,3-Benzodioxol-5-amine, N-methyl-수율 18%

실험 절차

The title compound was prepared from 3,4-(methylenedioxy)aniline and iodomethane by the procedure described in example 2 in 18% yield. 1H NMR (CDCl3): 6.67 (d, J=8.3, 1H), 6.25 (d, J=2.2, 1H), 6.04 (dd, J=2.2, 8.3, 1H), 5.85 (s, 2H), 3.50 (br s, 1H), 2.79 (s, 3H).

출처 및 근거

ORD 기록: ord-5fc52108de2a4c66899e1a5685813dc3
출처 데이터셋: uspto-grants-2002_10
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US06465472B1

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