Diethyl Ether → 2-Bromo-4-chlorobenzenediazonium tetrafluoroborate

HRID 992484

반응식

HRID 992484 반응식
[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[NH2:4].[H+].[B-:11]([F:15])([F:14])([F:13])[F:12].[N:16]([O-])=O.[Na+].C(OCC)C>CCO>[F:12][B-:11]([F:15])([F:14])[F:13].[Br:1][C:2]1[CH:8]=[C:7]([Cl:9])[CH:6]=[CH:5][C:3]=1[N+:4]#[N:16]

참가 물질

6

반응물 4

HCID 3283Diethyl EtherHCID 28118Tetrafluoroboric acidHCID 701102-Bromo-4-chloroanilineHCID 23668193Sodium Nitrite

생성물 1

HCID 184127642-Bromo-4-chlorobenzenediazonium tetrafluoroborate수율 96%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

A solution of 2-bromo-4-chloroaniline (10.0 g, 48.4 mmol) and HBF4 in EtOH (60 mL) kept at 0° C. was treated with an aqueous solution (20 mL) of NaNO2 (3.34g, 48.4 mmol). After completion of the addition, diethyl ether (200 mL) was added to the mixture. The solid was collected by filtration, washed with water and dried under high vacuum affording the title compound (14.2 g, 96%) as white crystals.

후처리

  1. customkept at 0° C.
  2. additionwas added to the mixture
  3. filtrationThe solid was collected by filtration
  4. washwashed with water
  5. customdried under high vacuum

출처 및 근거

ORD 기록
ord-455616b784b7483eb55eb365e0f0b005
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06469042B1

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