Sodium Hydroxide → 2-[N-(4-amidinophenyl)aminomethyl]benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(hydroxycarbonylmethyl) amide dihydrochloride
반응식
[ClH:1].Cl.[N:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]([CH2:32][C:33]([O:35]CC)=[O:34])[C:10]([C:12]1[CH:13]=[CH:14][C:15]2[S:19][C:18]([CH2:20][NH:21][C:22]3[CH:27]=[CH:26][C:25]([C:28](=[NH:30])[NH2:29])=[CH:24][CH:23]=3)=[N:17][C:16]=2[CH:31]=1)=[O:11].[OH-].[Na+]>>[ClH:1].[ClH:1].[N:3]1[CH:8]=[CH:7][CH:6]=[CH:5][C:4]=1[N:9]([CH2:32][C:33]([OH:35])=[O:34])[C:10]([C:12]1[CH:13]=[CH:14][C:15]2[S:19][C:18]([CH2:20][NH:21][C:22]3[CH:27]=[CH:26][C:25]([C:28](=[NH:29])[NH2:30])=[CH:24][CH:23]=3)=[N:17][C:16]=2[CH:31]=1)=[O:11]참가 물질
3
반응물 2
생성물 1
실험 절차
Prepared analogously to Example 10 from 2-[N-(4-amidinophenyl)-aminomethyl]-benzothiazol-5-yl-carboxylic acid-N-(2-pyridyl)-N-(ethoxycarbonylmethyl)-amide-dihydrochloride and sodium hydroxide solution.
출처 및 근거
- ORD 기록
- ord-a946da9599bf4d41999a1031c7493257