3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester → 3-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid

HRID 993485노트

반응식

HRID 993485 반응식
C([O:3][C:4](=[O:24])[C:5]1[CH:10]=[CH:9][C:8]([O:11][CH3:12])=[C:7]([O:13][CH2:14][CH2:15][C:16]2[CH:21]=[CH:20][C:19]([Cl:22])=[CH:18][C:17]=2[Cl:23])[CH:6]=1)C>C(O)C.[OH-].[Na+]>[Cl:23][C:17]1[CH:18]=[C:19]([Cl:22])[CH:20]=[CH:21][C:16]=1[CH2:15][CH2:14][O:13][C:7]1[CH:6]=[C:5]([CH:10]=[CH:9][C:8]=1[O:11][CH3:12])[C:4]([OH:24])=[O:3]

참가 물질

4

반응물 1

HCID 154803313-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester

생성물 1

HCID 154803323-[2-(2,4-Dichlorophenyl)ethoxy]-4-methoxybenzoic acid수율 73%

시약·촉매·용매 2

HCID 702Ethanol용매HCID 14798Sodium Hydroxide용매

실험 절차

A solution of 3.6 g (9.8 mmol) of 3-[2-(2,4-dichlorophenyl)ethoxy]-4-methoxybenzoic acid ethyl ester in 30 ml of ethanol and 5.4 ml of 2N sodium hydroxide solution was stirred at room temperature for 12 h. The precipitate was filtered off. The resulting solid was stirred with 5 ml of 2N HCl and filtered to give 2.44 g (73%) of the title compound.

후처리

  1. filtrationThe precipitate was filtered off
  2. filtrationfiltered

출처 및 근거

ORD 기록
ord-711d81b5cadd4bed9286c06dda74a7d1
출처 데이터셋
uspto-grants-2002_10
특허 번호
US06472562B1

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