Tetrahydrofuran → 1-[4-(1-Azido-1-methylethyl)phenyl]-2-(2-thienyl)ethanone

HRID 100214Notes

Reaction equation

HRID 100214 reaction equation
[CH2:31]1[O:32][CH2:33][CH2:34][CH2:35]1.[CH3:19][O:20][N:21]([C:22]([CH2:23][c:24]1[s:25][cH:26][cH:27][cH:28]1)=[O:29])[CH3:30].[CH3:1][CH2:2][CH2:3][CH2:4][Li:5].[N:6](=[N+:7]=[N-:8])[C:9]([CH3:10])([CH3:11])[c:12]1[cH:13][cH:14][c:15]([Br:18])[cH:16][cH:17]1>>[N:6](=[N+:7]=[N-:8])[C:9]([CH3:10])([CH3:11])[c:12]1[cH:13][cH:14][c:15]([C:22]([CH2:23][c:24]2[s:25][cH:26][cH:27][cH:28]2)=[O:29])[cH:16][cH:17]1

Participants

5

Reactant 4

HCID 8028TetrahydrofuranHCID 15029898N-methoxy-N-methyl-2-(thiophen-2-yl)acetamideHCID 538389621-(1-Azido-1-methylethyl)-4-bromobenzeneHCID 178418339Butyllithium

Product 1

HCID 866174631-[4-(1-Azido-1-methylethyl)phenyl]-2-(2-thienyl)ethanone

Sources & evidence

ORD record
ord-92298f64974949c0b92d1ab12313a078
Source dataset
Training data from https://doi.org/10.1039/C8SC04228D (2/10)

Reaction notes

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