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HuagongsheHuagongshe Chemistry Print Report · For research reference only
HRID 100235Generated: October 26, 2026

2-Chloromethyl-4-(beta-trimethylsilylethoxymethoxy)-naphthalene → (3RS,4RS)-1-benzyl-4-(4-fluoro-phenyl)-3-[4-(2-trimethylsilyl-ethoxymethoxy)-naphthalen-2-ylmethoxy]-piperidine

https://huagongshe.com/reaction/100235

Reaction equation

Participants

RoleNameHCIDCharge
Reactant2-Chloromethyl-4-(beta-trimethylsilylethoxymethoxy)-naphthaleneHCID 22126529—
Reactant(3RS,4RS)-1-benzyl-4-(4-fluoro-phenyl)-piperidin-3-olHCID 22126857—
Product(3RS,4RS)-1-benzyl-4-(4-fluoro-phenyl)-3-[4-(2-trimethylsilyl-ethoxymethoxy)-naphthalen-2-ylmethoxy]-piperidineHCID 22127049—

Provenance & Evidence

DOI10.1039/C8SC04228D
Source datasetTraining data from https://doi.org/10.1039/C8SC04228D (2/10)
ORD IDord-b37ac26fea564d78ab439912144f10cf
Source noteTraining data from https://doi.org/10.1039/C8SC04228D (2/10)