反应详情

An aqueous solution of 100 mg of 12-aminododecanol in 57% hydriodic acid was heated under reflux for one hour. To the reaction solution was added chloroform and the mixture was washed successively with water, a 10% aqueous solution of sodium thiosulfate and a saturated aqueous solution of sodium chloride and then dried over anhydrous magnesium sulfate. The solvent was distilled off and the residue thus obtained was chromatographed over a silica gel column to afford 171 mg of the title compound.

1. temperatureunder reflux for one hour
2. washthe mixture was washed successively with water
3. dry with materiala 10% aqueous solution of sodium thiosulfate and a saturated aqueous solution of sodium chloride and then dried over anhydrous magnesium sulfate
4. distillationThe solvent was distilled off
5. customthe residue thus obtained
6. customwas chromatographed over a silica gel column