Acetone → HCID 18796408, compound

HRID 1003322Notes

Reaction equation

HRID 1003322 reaction equation
[CH:1]([N:3]1[CH2:8][CH2:7][NH:6][CH2:5][CH2:4]1)=[O:2].[CH3:9][C:10]([CH3:12])=O>[C].[Pd]>[CH:1]([N:3]1[CH2:8][CH2:7][N:6]([CH:10]([CH3:12])[CH3:9])[CH2:5][CH2:4]1)=[O:2]

Participants

4

Reactant 2

HCID 180AcetoneHCID 821911-Piperazinecarboxaldehyde

Product 1

HCID 18796408HCID 18796408, compound

Reagents, catalysts & solvents 1

HCID 178418390HCID 178418390, compoundCatalyst

Procedure

To a solution of 1.02 g of formylpiperazine in 90 ml of acetone was added 0.1 g of 5% palladium carbon and the mixture was stirred under hydrogen atmosphere for 60 hours. The catalyst was filtered off and distilled off under reduced pressure to afford 1.31 g of the title compound.

Workup

  1. filtrationThe catalyst was filtered off
  2. distillationdistilled off under reduced pressure

Sources & evidence

ORD record
ord-209bc8714224470088ebf261be393b5d
Source dataset
uspto-grants-2000_04
Patent number
US06046201

Reaction notes

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