2-Amino-3-Hydroxypyridine → HCID 178476690, compound

HRID 1003427Notes

Reaction equation

HRID 1003427 reaction equation
[C:1]([OH:4])(=[O:3])[CH3:2].N=C1C(C)CCCN1.[NH2:13][C:14]1[C:19]([OH:20])=[CH:18][CH:17]=[CH:16][N:15]=1>>[C:1]([OH:4])(=[O:3])[CH3:2].[NH:13]=[C:14]1[CH:19]([OH:20])[CH2:18][CH2:17][CH2:16][NH:15]1

Participants

3

Reactant 2

HCID 281142-Amino-3-HydroxypyridineHCID 178475853HCID 178475853, compound

Product 1

HCID 178476690HCID 178476690, compound

Procedure

The method of preparation of 2-imino-3-methylpiperidine acetate, EXAMPLE 6, was used to convert 2-amino-3-hydroxypyridine to the title compound which was obtained as a white solid. The analysis of the product was found to be consistent with the proposed structure. m.p. 128-130° C. MH+=115; 1H NMR (D2O): δ4.34-4.28 (m, 1H); 3.20-3.10 (m, 2H); 2.05-1.50 (m, 4H); 1.71 (S, 3H).

Sources & evidence

ORD record
ord-83f041f532eb4392a16266f53c989ade
Source dataset
uspto-grants-2000_04
Patent number
US06046211

Reaction notes

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