HuagongsheHuagongshe Chemistry Print Report · For research reference only
Piperonylamine → 6-trifluoromethyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Piperonylamine | HCID 2723901 | — |
| Reactant | 6-(Trifluoromethyl)indole | HCID 2777523 | — |
| Product | 6-trifluoromethyl-3-(1,2,3,6-tetrahydropyridin-4-yl)-1H-indole | HCID 11242561 | 64% |
Reaction Steps
Beginning with 4.0 gm (22.0 mMol) 6-trifluoromethyl-1H-indole and 6.6 gm (43.0 mMol) 4-piperidone hydrochloride monohydrate, 3.7 gm (64%) of the title compound were recovered as a white solid.
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06046215 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-93eb397848fe4709b32a0238d196927e |
| Source note | uspto-grants-2000_04 |