Isopropylhydroxylamine → alpha-(3,4-Ethylenedioxyphenyl)-N-isopropylnitrone

HRID 1003661Notizen

Reaktionsgleichung

Reaktionsgleichung von HRID 1003661
[CH2:1]1[CH2:12][O:11][C:10]2[CH:9]=[CH:8][C:5]([CH:6]=O)=[CH:4][C:3]=2[O:2]1.[CH:13]([NH:16][OH:17])([CH3:15])[CH3:14]>>[CH2:1]1[CH2:12][O:11][C:10]2[CH:9]=[CH:8][C:5]([CH:6]=[N+:16]([CH:13]([CH3:15])[CH3:14])[O-:17])=[CH:4][C:3]=2[O:2]1

Komponenten

3

Edukt 2

HCID 78763IsopropylhydroxylamineHCID 2481272,3-Dihydro-1,4-benzodioxin-6-carbaldehyde

Produkt 1

HCID 85336065alpha-(3,4-Ethylenedioxyphenyl)-N-isopropylnitrone

Versuchsvorschrift

The title compound was prepared according to the procedure described in Example 11 using 3,4-ethylenedioxybenzaldehyde and N-isopropylhydroxylamine. The crude produce was purified by column chromatography over silica gel using ethyl acetate as the eluant. The title compound was isolated in 53% yield as a solid, m.p. 108.8° C. (Rf =0.31 on a silica gel plate using EtOAc as the eluant).

Aufarbeitung

  1. customThe title compound was prepared
  2. customThe crude produce
  3. customwas purified by column chromatography over silica gel

Quellen und Nachweise

ORD-Eintrag
ord-8b0d3989fe594837bc19b7d88ae6c040
Quelldatensatz
uspto-grants-2000_04
Patentnummer
US06046232

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