HuagongsheHuagongshe Chemistry Print Report · For research reference only
Isopropylhydroxylamine → alpha-(3,4-Ethylenedioxyphenyl)-N-isopropylnitrone
Participants
| Role | Name | HCID | Charge |
|---|---|---|---|
| Reactant | Isopropylhydroxylamine | HCID 78763 | — |
| Reactant | 2,3-Dihydro-1,4-benzodioxin-6-carbaldehyde | HCID 248127 | — |
| Product | alpha-(3,4-Ethylenedioxyphenyl)-N-isopropylnitrone | HCID 85336065 | — |
Reaction Steps
The title compound was prepared according to the procedure described in Example 11 using 3,4-ethylenedioxybenzaldehyde and N-isopropylhydroxylamine. The crude produce was purified by column chromatography over silica gel using ethyl acetate as the eluant. The title compound was isolated in 53% yield as a solid, m.p. 108.8° C. (Rf =0.31 on a silica gel plate using EtOAc as the eluant).
Provenance & Evidence
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| Patent number | US06046232 |
| Source dataset | uspto-grants-2000_04 |
| ORD ID | ord-8b0d3989fe594837bc19b7d88ae6c040 |
| Source note | uspto-grants-2000_04 |