HCID 18798258, compound → HCID 18798245, compound

Participants

Reaction Steps

50 mmol of 1,3,5-trimethyl-6-[(3-[4-(2-methoxy-4-nitrophenyl)-1-piperazinyl]propyl)amino]-2,4(1H,3H)-pyrimidinedione are reduced using hydrazine hydrate/Raney-Nickel in ethanol/water according to a known method. After purification by column chromatography and recrystallization from ethyl acetate, 73% of the title compound of m.p. 146-148° C. is obtained. The starting substance is the product of Example 14.

Provenance & Evidence